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Image Search Results
Journal: Toxics
Article Title: Physicochemical Transformations of Silver Nanoparticles in the Oro-Gastrointestinal Tract Mildly Affect Their Toxicity to Intestinal Cells In Vitro : An AOP-Oriented Testing Approach
doi: 10.3390/toxics11030199
Figure Lengend Snippet: Impact of non-digested and digested Ag NMs on HCT116 cell viability. Cell viability assessed by WST-1 assay 24 h after HCT116 cells were exposed to digested and non-digested Ag NPs ( a – c ), as well as HEC (no Ag) ( d ) and OGI fluid (no NMs) ( e ). PC refers to the positive control, i.e., amino-modified polystyrene nanoparticles (PSNH2) used at 100 µg/mL. Ag intracellular accumulation ( f ). HCT116 cells were exposed for 24 h to AgNKD, AgPVP and AgHEC, and intracellular Ag content was measured using ICP-MS. Values are the mean ± SD of three independent experiments with five replicates per experiment. Statistical significance, exposed vs. control, (*) p < 0.05, (***) p < 0.001, (****) p < 0.0001.
Article Snippet: In addition, we used one Ag NP produced by
Techniques: WST-1 Assay, Positive Control, Modification, Control